- UFC 2009: Undisputed (Xbox 360, PS3) ()
- UFC Personal Trainer (PS3)
- UFC Personal Trainer: The Ultimate Fitness System (XBox 360)
- UFC Undisputed 2010 (PS3)
- UFC Undisputed 2010 (Xbox 360, PS3, PSP) ()
- UGH (PC)
- UP (PS3 – PS2 - Wii - Xbox 360 - PC - DS – PSP) ()
- Ultima 7 (PC)
- Ultimate Marvel vs Capcom 3 (Vita)
- Ultimate Marvel vs. Capcom 3 (PS3 / Xbox 360) ()
- Ultimate Spider-Man (PC)
- Ultimate Spiderman (DS)
- Uncharted 2: Among Thieves (PS3)
- Uncharted 3: Drake's Deception (PS3)
- Uncharted Drake's Fortune (PS3)
- Uncharted: El Tesoro de Drake (PS3)
- Uncharted: Golden Abyss (Vita)
- Uncharted: el abismo de oro (Vita)
- Undead Knights (PSP)
- Unit 13 (Vita)
- Unlimited Soccer Manager (PC)
- Unreal (PC)
- Unreal 2: The Awakening (PC)
- Unreal Tournament (PC)
- Unreal Tournament (PS2)
- Unreal Tournament 2003 (PC)
- Unreal Tournament 2004 (PC)
- Unreal Tournament 3 (PC)
- Unreal Tournament 3 (PS3)
- Unsolved Crimes (DS)
- Untold Legends: Brotherhood of the Blade (PSP)
- Untold Legends: The Warrior's Code (PSP)
- Urban Assault (PC)
- Urban Chaos (Playstation)
- Urban Freestyle Soccer (PC)
- Urban Yeti (GB Advance)
- Urbz: Sims en la Ciudad (The Urbz: Sims in the City) (DS)
- uDraw Marvel Super Hero Squad: Comic Combat (PS3)
